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The Clinical Virology Team

Patrik Medstrand Professor Read about Patrik in the Research Portal Patrik´s publications                               Sara Karlson    Senior Laboratory Assistant   MSc. Biomedicine   Read about Sara in the Research Portal   Sara's publications " HIV research has always been very intriguing to me and this contributes to my long-term interest in the field. Working as a lab technician for three dif

https://www.virology.lu.se/clinical-virology/clinical-virology-team - 2025-11-19

The HIV Host Interactions Team

  Marianne JanssonPhD, Professor Read about Marianne in the Research PortalMarianne´s publications "My research is focused on understanding HIV host interactions and the impact these have on disease progression, by deciphering mechanisms behind protective and pathogenic immune responses in HIV-1 and HIV-2 infections. The goal is to contribute to optimized treatment and provide clues to how an effe

https://www.virology.lu.se/hiv-host-interactions/hiv-host-interactions-team - 2025-11-19

The Molecular Virology Team

Stefan Schwartz, PIRead about Stefan in the Research PortalNaoko Kajitani, researcherRead about Naoko in the Research PortalXiaoxu Cui, graduate studentRead about Xiaoxu in the Research PortalChengyu Hao, graduate studentRead about Chengyu in the Research PortalJohanna Jönsson, graduate studentRead about Johanna in the Research PortalYunji Zheng, graduate studentRead about Yunji in the Research Po

https://www.virology.lu.se/molecular-virology/molecular-virology-team - 2025-11-19

Projects

Project I Studies on the impact of HIV-2 low level viremia on immunopathogenesis Project II Studies on immune responses and viral reservoirs in HIV-2 extreme elite controllers  Project III Studies on type 1 interferon signaling in HIV-1 and HIV-2 infections  Project IV Studies on the incorporation and structure of HIV-2 envelope glycoproteins  Areas Project I Studies on the impact of HIV-2 low lev

https://www.virology.lu.se/hiv-host-interactions/projects - 2025-11-19

Contact

Patrik Medstrand, Professor E-post: patrik [dot] medstrand [at] med [dot] lu [dot] se (patrik[dot]medstrand[at]med[dot]lu[dot]se) Professor vid Klinisk virologi, Malmö Telefon: +46 46 222 14 89 Mobil: +46 70 841 57 97 Rumsnummer: BMC B1354b Professor vid EpiHealth: Epidemiology for Health Chef vid Klinisk virologi, Malmö Forskargruppschef vid Klinisk virologi, Malmö

https://www.virology.lu.se/clinical-virology/contact - 2025-11-19

Marianne Jansson

HIV-1 and HIV-2 host interactions - - Lund University Karlsson I, Tingstedt JL, Sahin GÖ, Hansen M, Szojka Z, Buggert M, Biague A, Da Silva Z, Månsson F, Esbjörnsson J, Norrgren H, Medstrand P, Fomsgaard A*, and Jansson M*; Sweden-Guinea-Bissau Cohort Research Group. Cross-Reactive Antibodies With the Capacity to Mediate HIV-1 Envelope Glycoprotein-Targeted ADCC Identified in HIV-2-Infected Indivi

https://www.virology.lu.se/hiv-host-interactions/marianne-jansson - 2025-11-19

Covers & Highlights

For many double stranded (ds) DNA viruses the viral genome is actively packaged into the virus capsid by a powerful molecular motor. This results in an energetically unfavorable state of the packaged genome, creating tens of atmospheres internal pressure inside the virion. Using a new calorimetric assay to determine the activation energy barriers associated with genome loss in response to elevated

https://www.virus-biophysics.lu.se/covers-highlights-0 - 2025-11-19

Covers, Movies and Highlights

 For many double stranded (ds) DNA viruses the viral genome is actively packaged into the virus capsid by a powerful molecular motor. This results in an energetically unfavorable state of the packaged genome, creating tens of atmospheres internal pressure inside the virion. Using a new calorimetric assay to determine the activation energy barriers associated with genome loss in response to elevate

https://www.virus-biophysics.lu.se/covers-movies-and-highlights - 2025-11-19

Open positions

ALEX EVILEVITCH RESEARCH GROUP We are always interested in reviewing applications from MSc students, prospective PhD students and postdocs.   Project description    Herpesviruses are a leading cause of human viral disease. Herpesviruses consist of a double-stranded DNA genome contained within a protein shell, termed the capsid, that is surrounded by an unstructured protein layer and a lipid-envelo

https://www.virus-biophysics.lu.se/open-positions-0 - 2025-11-19

Research Overview

Virus Biophysics Virus Biophysics is a rather new field that seeks to define the physical mechanisms controlling virus development. This knowledge can provide information essential to the rational design of new antiviral strategies with less specificity for a limited number of viruses. Furthermore, biological and physical simplicity relative to other biological systems have made viruses an attract

https://www.virus-biophysics.lu.se/research-overview - 2025-11-19

Homepage

News and Events January 9, 2024 , Physics World "Viruses change structure at the temperature of the human body to better infect us". If you want to know in simple words a possible mechanism of viral genome delivery, read more in this link (it opens a new webpage).November 8, 2023,  Lund University press release on our pioneering study published in PNAS showing how temperature triggers release of v

https://www.virus-biophysics.lu.se/node/137 - 2025-11-19

Movies & Artwork

Herpes Simplex 1 pressurized DNA release into a cell nucleus. DNA packaging and capsid reinforcement  Illustration and poem inspired by graduate student Krista Freeman's contributions to “The Invisible Jazz Experimental Laboratories”, hosted by The Space Upstairs in Pittsburgh, PA."I've optimized my eyes to fill my brain with dissonance in a balance. The information is a bomb, every fact a potenti

https://www.virus-biophysics.lu.se/movies-artwork - 2025-11-19

Methods and Techniques

Our Biophysical ToolsOur research group investigates mechanics of viral replication, virus-host interactions, virus assembly and disassembly within the host. Specifically, we investigate energetics, structure and mobility of the intra-capsid genome as well as mechanical properties of viral capsids, influenced by changes in physiological environment that are important for viral replication. Main to

https://www.virus-biophysics.lu.se/methods-and-techniques - 2025-11-19

People

  Principal Investigator: Alex Evilevitch, PhDProfessor of Cell Biology Email: Alex [dot] Evilevitch [at] med [dot] lu [dot] se   Lab photos    Postdocs   José Ramón Villanueva Valencia, PhDEmail: jose_ramon [dot] villanueva-valencia [at] med [dot] lu [dot] se (jose_ramon[dot]villanueva-valencia[at]med[dot]lu[dot]se)    Santosh Gawali, PhD Email: santosh [dot] gawali [at] med [dot] lu [dot] se   G

https://www.virus-biophysics.lu.se/people - 2025-11-19